A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

The Department of Radiology at Michigan Medicine of the University of Michigan has an immediate opening within the Center for Molecular Imaging for a Synthetic Organic Chemist postdoctoral fellow. The candidate is required to have a strong background in organic synthesis and a demonstrated ability to work independently in the design and development of small molecule candidates of biological interest in oncology and immune-suppressive agents. High proficiency in compound isolation techniques (low pressure chromatography, HPLC) and characterization (NMR, MS, LCMS, HPLC) and familiarity with literature search methodology (e.g. SciFinder, Beilstein) is also required. A background in utilizing computational molecular docking software would also be beneficial. The candidate is expected to be a good team player and have excellent oral and written communication skills.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

Synthetic Organic & Medicinal Chemistry Independently design chemical routes and select appropriate reaction conditions for individual steps. Conduct multistep chemical syntheses from mg to Kg scale.

Optimize chemical routes and reactions to set deliverables up to multi-kilogram scale. Participate in external and internal chemistry collaborations. Work up, purify, and characterize all synthesized compounds and prepare submissions for in vitro and in vivo studies. Maintain Chemistry Lab Notebook and comply with notebook best practices per university policies.

Collaboratively design studies. Maintain synthetic and analytical lab equipment. Collect and interpret all data for all synthesized compounds and intermediates: Any form/type of NMR; Mass spectrometry; HLPC-UV purity. Computational work with Schrodinger molecular docking software or equivalent. Maintain EHS lab standards including manage waste streams, conduct peroxide testing, keep work areas organized and clean, update and maintain labels on chemical stocks, maintain the chemical inventory list, maintain and order materials for the lab. Reporting requirements include preparation of publications patent applications submission of abstracts and present conference posters and talks. 

The applicant must hold a PhD degree in Synthetic Organic or Medicinal Chemistry or a related field in the synthesis of kinase inhibitors.

Applicants with a PhD in Synthetic Organic or Medicinal Chemistry.

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

One-year postdoc with option to renew

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

The University of Michigan is an equal employment opportunity employer.