A Research Associate II temporary position is available in a dynamic research laboratory in the Department of Radiology at Michigan Medicine. Our group, led by Dr. Stefanie Galban, focuses on developing and establishing mouse models of various malignancies recapitulating human disease to develop novel therapies, including gene therapy and imaging technologies. Central to our studies is the lethal pediatric brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG), particularly targeting cancer stem cells to address treatment resistance and identify new therapeutic paradigms in this disease. Our laboratory is surrounded by a rich research environment at the Center for Molecular Imaging and the Rogel Cancer Center. This position will support our investigations of  mechanisms of molecularly targeted therapies utilizing imaging in cell cultures and mouse models. The research will involve molecular and cell biology procedures, gene editing techniques, protein analysis, DNA and RNA sequencing, fluorescence and bioluminescence imaging, and multi-modality imaging studies in mouse models of various cancers.

The candidate is expected to perform experiments to accomplish lab goals and critically analyze data. The research assistant will be expected to coordinate efforts with researchers in the Galban lab. The candidate must be open to a flexible schedule to accommodate times for animal imaging and varying treatment schedules.

Members of the Galban Laboratory work in a highly collaborative research environment with leading experts in oncology and imaging. Our goal is to motivate and train research assistants, students and postdocs across disciplines to address new and challenging problems in cancer and develop novel therapies.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

60%- Molecular and cell biology animal experiments

• Perform experiments
• Coordinate research efforts with researchers in other scientific disciplines
• Cell-based assays
• Gene editing
• Molecular biology, western blotting, qRTPCR
• DNA and RNA sequencing
• scRNA sequencing
• Immunohistochemistry/multiplex

10%- Imaging experiments

• Conduct multi-modality imaging studies in mouse models of various cancers
  MRI, CT, bioluminescence and fluorescence imaging

30%- Technical

• Analyze experimental data and interpret results to write summary reports and findings
• Prepare figures for manuscripts

Highly motivated and enthusiastic individual with a MS, MD/PhD or PhD background in cell and molecular biology, along with a record of research excellence as demonstrated by peer-reviewed publications and scientific productivity. The candidate must work well in a team of multidisciplinary researchers, have excellent organizational and communications skills in English, and competence in word processing and spreadsheet software.

BSRB

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal employment opportunity employer.