A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

This position will serve as a Clinical Research Coordinator Senior supporting the University of Michigan Health Network PRecision Oncology Program, Mi-PRO, within the University of Michigan Rogel Cancer Center. Mi-PRO is a systemwide precision oncology initiative designed to expand access to advanced tumor molecular profiling, genomic-informed clinical trial matching, virtual molecular tumor board review, genetic counseling, pharmacy support, and precision oncology research across the UM Health network.

The Clinical Research Coordinator will play a key role in supporting Mi-PRO?s mission to ensure that patients with advanced cancer have equitable access to personalized, data-driven cancer care informed by next-generation sequencing and other molecular profiling technologies. This position will provide mentorship, clinical research coordination, patient screening, data management, and operational support for precision oncology research workflows, with particular emphasis on leading clinical research teams in identifying patients who may be eligible for genomically informed clinical trials and tracking trial-matching outcomes across UM Health.

This role will work closely with Mi-PRO leadership, oncology providers, molecular pathology, informatics, genetic counseling, pharmacy, the Oncology Clinical Trial Support Unit, clinical trials teams, and participating UM Health sites. The coordinator will support and oversee activities related to clinical trial screening, maintenance of trial-matching databases, review of clinical and molecular information, virtual molecular tumor board workflows, regulatory documentation, and program evaluation.

The University of Michigan Rogel Cancer Center is an NCI-Designated Comprehensive Cancer Center and a member of the National Comprehensive Cancer Network. We are among the top-ranked national programs in cancer research and patient care, with members holding substantial annual direct research funding. Our mission is to reduce the cancer burden and improve cancer outcomes through research, innovation, and transdisciplinary collaboration. Through Mi-PRO, this position will contribute to a growing precision oncology infrastructure that supports breakthrough therapies, clinical trial access, and innovative cancer research across Michigan.

This Clinical Research Coordinator position will provide coordination for multiple clinical research activities ranging from moderate to complex. Coordinator experience and mastery of all job duties from the CRC-Intermediate position on the Michigan Medicine CRC Career Ladder is required for appointment at the Senior level. This position should be able to perform tasks and make decisions independently, consistently, and accurately, and demonstrate an advanced level of expertise across required skills and abilities, resulting in high-quality work.

It is expected that this position will be able to apply clinical research coordination skills to a broad range of precision oncology activities, navigate available resources appropriately, contribute to development and effectively use all tools and job aids, and operate electronic clinical research technologies with proficiency. This position can perform the majority of tasks independently, conduct quality checks of their own work and others, identify appropriate resources and support, provide mentorship to clinical research coordinators and teams at multiple locations, and discern when to escalate issues requiring additional intervention. 

Characteristic Duties and Responsibilities

Independent knowledge, skills, and abilities within all eight competency domains is expected:

• Scientific Concepts and Research Design 
• Ethical Participant Safety Considerations 
• Investigational Products Development and Regulation 
• Clinical Study Operations, including Good Clinical Practice 
• Study and Site Management 
• Data Management and Informatics 
• Leadership and Professionalism 
• Communication and Teamwork

Due to the complex nature of oncology clinical research and precision oncology care, this position will work as part of a multidisciplinary team that may include clinical research coordinators, data managers, regulatory staff, oncology providers, molecular pathology, informatics, genetic counseling, pharmacy, and clinical trial teams. The Clinical Research Coordinator hired for this posting will specialize in precision oncology clinical research coordination, including clinical trial screening, molecularly informed trial matching, data tracking, and support for Mi-PRO operational workflows.

Examples of duties a successful candidate in this role will perform include:

Clinical Research Coordinator - Senior

• Demonstrates understanding of clinical research protocols, eligibility criteria, study procedures, and precision oncology workflows.
• Reviews patient clinical information, diagnosis, disease status, prior therapies, biomarker results, next-generation sequencing reports, and other molecular profiling results to support preliminary clinical trial screening.
• Supports identification of patients who may be eligible for genomically informed, targeted therapy, or precision oncology clinical trials.
• Uses clinical research systems, electronic medical records, clinical trial management systems, and trial-matching tools, such as MatchMiner or similar platforms, to support patient screening and trial matching.
• Maintains Mi-PRO clinical trial screening logs, trial-matching databases, and patient tracking tools across multiple sites.
• Tracks screening outcomes, including potential trial matches, referrals to disease-specific clinical trial teams, eligibility determinations, enrollment outcomes, and reasons for non-enrollment when available.
• Collaborates with oncology providers, disease-specific research teams, the Oncology Clinical Trial Support Unit, and participating UM Health sites to facilitate appropriate handoffs for potential clinical trial evaluation.
• Demonstrates the ability to anticipate and mitigate potential protocol non-compliance or workflow gaps, develops tools and processes to address
• Describes protocol structure and explains how to interpret study requirements to support study compliance.
• Demonstrates accurate implementation of protocol procedures and research workflows.
• Performs study procedures and research coordination activities with minimal supervision.
• Triages subject, provider, or workflow issues appropriately and escalates complex concerns to the appropriate team member, CRC-Lead, project manager, investigator, or program leadership.
• Supports operational workflows for the Mi-PRO virtual molecular tumor board, including case tracking, preparation of relevant clinical and molecular information, documentation of recommendations, and follow-up of trial referral opportunities.
• Coordinates with molecular pathology, informatics, genetic counseling, pharmacy, oncology providers, and research teams to support timely review and follow-up of precision oncology recommendations.
• Supports collection, entry, verification, and quality control of clinical, genomic, and trial-related data for research, reporting, quality improvement, grant submissions, abstracts, presentations, and manuscripts.
• Assists with regulatory activities, including preparation and maintenance of IRB materials, amendments, continuing reviews, protocol updates, and required reporting, as applicable.
• Ensures appropriate documentation of screening activities, consent status when applicable, protocol deviations, and other required research records.
• Maintains confidentiality and security of sensitive patient, clinical, genomic, and research data in accordance with HIPAA, institutional policies, human subjects research requirements, and applicable regulations.
• Participates in quality assurance activities, audits, monitoring visits, and program reviews as needed. 
• Supports development and refinement of Mi-PRO workflows, standard operating procedures, training materials, and educational resources.
• Assists in identifying barriers to clinical trial enrollment and contributes to workflow improvements aimed at expanding equitable access to precision oncology research.
• Explains the role of the Clinical Trial Support Unit and related research infrastructure in supporting study activation, participant tracking, clinical trial referral, and subject visit billing when applicable.
• This position reports directly to a CRC-Project Manager and the clinical directors of the MI-PRO program.

CRC Senior:

Education-

• Bachelor's degree with direct related experience in clinical research

• Professional Certification through ACRP or SoCRA

• External hires require certification within 6 month probationary period

Experience-

• 5+ years directly related clinical research experience

• 2+ years of experience at CRC Intermediate or above or external equivalent experience 

Approvals-

• CRC Advisory Committee approval

CRC Intermediate (underfill):

Education-

• Bachelor's degree with direct related experience in clinical research
• Professional Certification through ACRP or SoCRA
• External hires require certification within 6-month probationary period

Experience-

• 3+ years directly related clinical research experience

1+ years of experience at CRC Associate or above or external equivalent experience 

CRC Senior:

• 9+ years of direct related experience

• 4+ years of oncology research experience

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world?s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled any time after the minimum posting period has ended.

The University of Michigan is an Equal Opportunity Employer. We are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants, including protected veterans and individuals with disabilities.