Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Being part of something greater, of serving a larger mission of discovery and care ? that's the heart of what drives people to work at Michigan. In some way, great or small, every person here helps to advance this world-class institution. It's adding a purpose to your profession. Work at Michigan and become a victor for the greater good.

- Establish and analyze Tgfbi knock out and transgenic mice +/- induction of type and type diabetes mellitus. This includes analyses of kidney tissue by immunohistochemistry (IHC), immunofluorescence (IF), RNA-sequencing, scRNA-seq and spatial transcriptomics; analysis or urine and blood samples.

- Perform tissue culture experiments which includes exposure of human and non-human cultured cells to recombinant TGFBI and inhibitors of TGFBI and other related molecules, and analysis of cellular phenotype by detachment / adhesion assays, Western Blotting, IHC/IF, RNA-seq, qrt-PCR, co-IP, pull-down assay and other molecular biology assays.

- Interrogate proteins in human and mouse urine and blood samples using ELISA and other molecular biology assays. Perform statistical analysis of findings (with support from biostatistician).

- Preparation of manuscripts, presentations, meeting abstracts, grant proposals. 

PhD in Molecular Biololgy or related fields.
Skills and experience with basic molecular methods including but not limited to processing/preserving/analyzing mammalian organ tissue (mice), culture of epithelial cells, immunohistochemistry (IHC), immunofluorescence (IF), Western Blotting, RNA-sequencing, ELISA. 
Willingness and ability to perform experimental work with rodents (mice). 
Experience with mouse work is preferred.

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled any time after the minimum posting period has ended.

The University of Michigan is an equal employment opportunity employer.

The University of Michigan is an equal employment opportunity employer.