A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

The scientist will be expected to work closely with the PI and other lab personnel in the implementation of this research program. A BS with some experience in cell biology, developmental biology, immunology, physiology, or related field is required. Outstanding organizational skills, attention to detail, ability to work hard and be flexible in a fast-paced environment, and ability to get along with other lab members are important. Prior experience with rodents, cell culture, microscopy, RNA/qPCR, western blotting, computational biology, and/or flow cytometry would be helpful but is not required. Motivated candidates will be quickly trained in all these methods. Minor responsibilities will include lab organization. Excellent opportunity for individuals interested in studying stem cells and tissue regeneration. We support transition to graduate/medical school in the future.

Excellent opportunity for individuals interested in studying stem cells and tissue regeneration as well as immune-epithelial crosstalk. Projects range from basic mechanistic to translational. Opportunities to learn cutting-edge techniques, including organoid culture and scRNAseq. Opportunities for career development, including manuscript and grant writing and oral presentation, mentorship, attending international conferences, interacting with renowned scientists who are collaborators.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Our lab is interested in understanding the mechanisms by which the lung epithelium responds to injury. We study mechanisms of injury/inflammation and regeneration after injury. Epithelial injury and a failure of epithelial regeneration is thought to drive the development of lung diseases such as ARDS (including COVID-19), fibrosis, and emphysema. Specifically, we are exploring the mechanisms underlying proliferation and differentiation of alveolar epithelial progenitor or stem cells. We have identified ?-catenin, HIF, and TGF? signaling as important drivers. We also study the epithelial inflammatory and host defense responses to bacterial and viral infection, specifically epithelial-immune cell crosstalk. We use mouse and cell culture models to study mechanisms. The mouse work involves lineage tracing and inducible cell-specific gene deficient mice, and primary epithelial cell culture/organoid work allows us to further dissect mechanism. We use confocal imaging, immunostaining, fluorescence in situ hybridization (FISH), single cell RNA sequencing, proteomics, and flow assisted cytometry sorting (FACS). We aim to address important questions and make novel discoveries that significantly enhance out understanding of lung biology and disease. We hope that our discoveries may ultimately lead to the development of therapies for infectious, inflammatory, and fibrotic lung diseases.

Lab Website: https://sites.google.com/view/rachelzemanslab/home

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

• Performs experimental procedures in one or more areas of work under the supervision of higher level research staff. 
• Helps clean up after experiments.
• Administers tests, gathers data, records observations and measurements.
• Sets up and operates laboratory equipment
• Performs routine computations and computer analysis
• Responsible for completing lab documentation for inspections

• Research Lab Tech Intermediate: HS Diploma or Assoc Degree and 1+ years experience.
• Research Lab Tech Senior: Bachelor's degree and 1+ years experience

• Research Lab Tech Intermediate: Bachelor's Degree preferred.

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.

This is a 1 year term-limited appointment. At the end of the stated term, your appointment will terminate, and will not be eligible for Reduction-in-Force (RIF) benefits. This term-limited appointment does not create a contract or guarantee of employment for any period of time as you will remain subject to disciplinary or other performance measures, up to and including termination, at the will of the University in accordance with existing University policy and standards for employee performance and conduct.

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal opportunity/affirmative action employer.